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Our goal is to help millions of cluster headache patients access safe, effective pain relief treatments as soon as possible.
Despite being considered the most painful condition known to medicine, and affecting about 3 million adults every year, cluster headache is severely underfunded. Even in wealthy nations with advanced healthcare, hundreds of thousands still experience torture-like suffering every year.
Sometimes I think we — the ones who suffer from cluster headaches — should be invited to help pastors when they preach about hell.
Why? Because we’ve experienced something most people can’t even imagine. Every time an attack strikes, it’s like catching a glimpse of hell — not in some distant, spiritual sense, but in the form of unbearable, all-consuming pain.
The agony is so intense, so relentless, it strips away everything: thoughts, dignity, time. It feels like being locked inside your own head while something tries to tear it apart from the inside, and all you can do is hold on.
S. K., cluster headache patientWe believe we can make a difference, and donations make our work possible. As a lean operation, we can put significant additional funding to use immediately.
If you want to support our efforts, you can donate via card, bank transfer, PayPal, Apple Pay, Google Pay, Venmo, crypto, stocks, or DAF. Donations are tax-deductible in the US.
A global network of organizations supports our mission, including Clusterbusters; our research has been published in a Nature Portfolio journal; and our open letter has been signed by leading figures including philosopher Peter Singer, psychopharmacologist Robin Carhart-Harris, neurologist Christopher Gottschalk, and writer Scott Alexander.
Considering a larger gift?
If you're thinking about a significant donation, we'd welcome the chance to talk it through with you personally, so you know where your money would go and what it would unlock.
Alfredo Parra, PhD
Co-Founder & Director
You can earmark your donation for a specific program. On request, we're happy to walk you through our cost-effectiveness analysis and our room-for-funding plans, so you can see the reasoning behind every dollar.
Support other organizations
We also strongly recommend donating to Clusterbusters. For over 25 years, Clusterbusters have been the driving force behind psychedelic treatments for cluster headache, turning anecdotal patient reports into peer-reviewed medical research. They have directly helped thousands of cluster headache patients worldwide, and their website is the most comprehensive resource for cluster headache patients seeking information about existing and emerging treatments.
Additionally, consider supporting the Organisation for the Prevention of Intense Suffering. Beyond publishing academic and policy papers, their advocacy work resulted in Health Canada granting a cluster headache patient legal access to psilocybin for the first time in 2024. You can learn more about their work here.